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Anticancer Activity of Bitter Melon-Derived Vesicles Extract against Breast Cancer
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She seemed sweet, kind of clueless but sweet. As soon as i looked at him he looked at me back and kept eye contact with me for what felt like hours, untill i finally looked away and kept walking. As far as head and neck cancer is concerned, the bitter gourd bioactive secondary metabolite momordicine-I reduced human head and neck cancer cell viability in a dose-dependent way, with negligible side effects on non-cancerous cells, constraining c-Met and its downstream signaling molecules via the inhibition of Signal Transducer and Activator of Transcription 3 STAT3 in head and neck cancer cells, and it reduced head and neck cancer tumor growth in nude mice xenograft models, involving c-Met and downstream signaling [ 13 ]. New Reading List. Technical Details isolated kuguacin J from bitter melon leaves and reported that this active component sensitized KB-V1 cells to vinblastine and paclitaxel by upregulating the intracellular accumulation of rhodamine, calcein AM, and [ 3 H]-vinblastine, as well as blocking the incorporation of [ I]-iodoarylazidoprazosin into P-glycoprotein in a concentration-dependent manner [ 40 ]. Add Cancel. Delivery cost, delivery date and order total including tax shown at checkout.
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Altogether, these results indicate that bitter melon and its bioactive components may successfully inhibit breast cancer development and progression both in vitro and in vivo.New Reading List.